Pattern of circulating microparticles in chronic heart failure patients with metabolic syndrome: Relevance to neurohumoral and inflammatory activation

The signature of circulating microparticles in heart failure patients with metabolic syndrome

The role of pattern of circulating endothelial cell-derived microparticles, platelet-derived microparticles (PMPs), and monocyte-derived microparticles (MMPs) in metabolic syndrome (MetS) patients with chronic heart failure (CHF) is not still understood. The aim of the study was to investigate a pattern of circulating microparticles (MPs) in MetS patients with CHF in relation to neurohumoral an...

Impaired Pattern of Endothelial Derived Microparticles in Heart Failure Patients

Chronic heart failure (CHF) remains a leading cause of cardiovascular morbidity and mortality worldwide that is characterized pandemic features. Metabolic diseases, neurohumoral state, and systemic inflammatory response are considered the origin of microvascular endothelial cell inflammation that leads to development of CHF and supporting cardiac remodelling and vascular dysfunction. Endothelia...

The Immune Phenotypes of Circulating Microparticles with in Chronic Heart Failure Patients with Metabolic Syndrome

Dietary Approaches to Stop Hypertension (DASH) Eating Plan: Beyond the Hypertension

Background and Objectives: Dietary Approaches to Stop Hypertension (DASH) eating pattern, a diet rich in fruits, vegetables, whole grains and low-fat dairy with a reduced content of sodium, saturated fat, and total fat is introduced as an appropriate diet for hypertension. This eating pattern was basically designed to normalize blood pressure in patients with hypertension, and a large body of d...

Circulating Endothelial-Derived Apoptotic Microparticles in the Patients with Ischemic Symptomatic Chronic Heart Failure: Relevance of Pro-Inflammatory Activation and Outcomes

BACKGROUND Endothelial-derived apoptotic microparticles (EMPs) play a pivotal role in endothelial dysfunction in hronic Heart Failure (CHF). OBJECTIVES The present study aimed to evaluate the association between EMPs and pro-inflammatory biomarkers, clinical status, and outcomes in the patients with ischemic CHF. PATIENTS AND METHODS This study was conducted on 154 patients with ischemic sy...